Cytoplasmic retention
WebDec 7, 2024 · Due to its potent cytoplasmic retention activity, we named this region (352–357 aa) Cytoplasmic Anchoring Signal, CAS. To further elucidate the working mechanism of the CAS motif, we generated a pair of stable HeLa cell lines that inducibly expressed either the wild type GDOWN1 (WT-Venus) or its CAS mutant ( mCAS -Venus) … WebOct 13, 2024 · If Pbs2 had a cytoplasmic retention or nuclear export role, then we might expect that even inactive Hog1–GFP accumulates in the nucleus in pbs2Δ strains. If Pbs2 were to enable the import of Hog1 not only by normal basal level phosphorylation but also by functioning as a carrier, then we could expect a nuclear exclusion signal of Hog1 in ...
Cytoplasmic retention
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WebThe cytoplasmic retention of the precursor molecule is controlled by a small region in its C-terminal part. We show that this region is responsible for the observed lack of … WebJul 19, 2004 · Hence the activity control and intracellular localization of HsfA2 is an important aspect of plant performance in the daily cycles of heat stress and recovery experienced in a natural surrounding. In this study, we present results about a novel function of tomato Hsp17.4-CII as cytoplasmic retention factor and corepressor of HsfA2.
WebJun 6, 2014 · The results introduce a new paradigm where cytokine treatment prolongs nuclear retention simultaneous with decreasing rather than increasing the rate of nuclear import. ... It would thus appear that the C-terminal tail of STAT3α contributes to cytoplasmic retention of STAT3 in the cytoplasm under basal conditions, with S727 within it helping ... WebSpecialty. Immunology. Cytokine release syndrome ( CRS) is a form of systemic inflammatory response syndrome (SIRS) that can be triggered by a variety of factors …
WebJun 1, 2024 · Here, we report that Mastermind-like 1 and 2 (MAML1/2) are indispensable for YAP/TAZ nuclear localization and transcriptional activities. Ectopic expression or depletion of MAML1/2 induces nuclear translocation or cytoplasmic retention of YAP/TAZ, respectively. Additionally, mutation of the MAML nuclear localization signal, as well as its …
WebAug 1, 1999 · The MA domain of these viruses contains a "cytoplasmic targeting and retention signal (CTRS)" which is necessary for the intracytoplasmic assembly of virus particles. 186, 190 A single amino acid ...
WebNov 6, 2024 · AE1 coexpression could reduce the ER/Golgi retention of GPB, but not of GPBtail or GPBhead. ... Most C-terminal, cytoplasmic residues of GPA (25 amino acids) were omitted. The cytoplasmic region of GPA has been reported to support AE1 forward trafficking . The pre-TMD of GPA (residues 61–70) supports the anion transport activity … balenciaga b parisWebDec 7, 2024 · One was the intrinsic nature of cytoplasmic retention determined by GDOWN1’s CAS motif, the other was the artificial driving force for its accumulation in the … arirang korean restaurant columbia scWebApr 1, 2006 · Nucleo-cytoplasmic distribution of β-catenin is regulated by retention. J Cell Sci (2006) 119 (7): 1453–1463. β-catenin is the central signalling molecule of the … balenciaga broken trainersWebFeb 1, 2003 · The interphase cytoplasmic location of cyclin B1/Cdc2 reflects continuous, albeit slow, nuclear import and much more rapid nuclear export. In contrast, the sudden nuclear accumulation of the complex before entry into mitosis reflects a marked increase in the import rate, with a concomitant inhibition of cyclin B1 nuclear export. balenciaga b perfume ukWebThe cytoplasmic retention of the precursor molecule is controlled by a small region in its C-terminal part. We show that this region is responsible for the observed lack of DNA binding of the p50 precursor and controls the extent of … balenciaga brand wikipediaWebRetention of the Unspliced RNAs and Transcriptional Down-Regulation of the Splicing-Defective Genes Andrea B. Eberle, Viktoria Hessle, Roger Helbig, Widad Dantoft, Niclas Gimber, Neus Visa* ... site of translation in the cytoplasm. The transcripts are associated with different types of RNA-binding proteins throughout the gene expression pathway ... balenciaga b perfume sephoraWebJan 21, 1997 · M-phase promoting factor or maturation promoting factor, a key regulator of the G 2 → M transition of the cell cycle, is a complex of cdc2 and a B-type cyclin. We have previously shown that Xenopus cyclin B1 has five sites of Ser phosphorylation, four of which map to a recently identified cytoplasmic retention signal (CRS). The CRS appears to … balenciaga brand image